What is the connection between blood sugar spikes and cancer development?
Allulose StoreTHE blood sugar spikes and the cancer development Several interrelated mechanisms are known, mainly related to persistently high blood sugar levels (hyperglycemia) and insulin resistance:
• High insulin levels and insulin resistance:
Regular blood sugar spikes can lead to insulin resistance in the long term, when the body needs more and more insulin to regulate blood sugar levels.
Insulin is a growth hormone that can also stimulate the growth of cancer cells. Thus, persistently high insulin levels can promote the growth of cancer cells and inhibit programmed cell death (apoptosis) 1 2 5 .
• Chronic inflammation:
Blood sugar spikes and persistent hyperglycemia trigger chronic inflammation in the body.
This inflammatory environment can promote cellular damage, mutations, and increase the risk of cancer 2 .
• Increased cancer risk in diabetes:
Large-scale Hungarian studies have shown that people with diabetes, especially type 2 diabetes, have a significantly higher incidence of pancreatic, liver, kidney, colon, prostate and breast cancer than the healthy population 2 5 .
• Metabolism of cancer cells:
The main energy source of cancer cells is glucose, and due to their faster metabolism, they are particularly sensitive to changes in blood sugar levels.
Persistently high blood sugar levels can create a favorable environment for cancer cell growth 6 .
• Temporal relationship:
Research suggests that the risk of cancer begins to increase even before the diagnosis of diabetes and peaks one to two years after diagnosis, reinforcing the role of insulin resistance and hyperglycemia in cancer development 5 .
